Plenvu Prep Instructions

The following medications should be held as instructed prior to procedure:

Phentermine: Adipex-P, Qsymia, and Lomaira (Daily) – These medications will need to be stopped seven (7) days prior to your procedure.

All GLP-1 medications, including those listed below, will need to be stopped seven (7) days prior to your procedure if you are on a weekly dose or the day of your procedure if you are on a daily dose.

• Dulaglutide: Trulicity (Weekly)
• Exenatide: Bydureon (Weekly) and Byetta (Daily)
• Liraglutide: Victoza (Weekly) and Saxenda (Daily)
• Lixisenatide: Adlyxin (Daily) and Soliqua (Daily)
• Semaglutide: Ozempic (Weekly), Wegovy (Weekly) and Rybelsus (Daily)
• Tirzepatide: Mounjaro (Weekly) and Zepbound (Weekly)

• If you are taking a blood thinner prescribed by a physician (such as Coumadin, Plavix, Effient, Eliquis or Ticlid). Your gastroenterologist will need to determine if these medication dosages require adjustment prior to the procedure. Failure to properly adjust these medications may result in cancellation of your procedure. You may continue to take Aspirin as usual.
• If you are having chest pain, undergoing cardiac testing, or have pending cardiac tests. (IMPORTANT: Please notify us before you begin to prep for your procedure.)
• If you have had any recent hospitalizations.
• If you have ever had excessive bleeding after an operation or problems with anesthesia.
• If there is a possibility you are pregnant.

• DO NOT take iron, diet pills (Phentermine, Adipex or Qsymia), GLP weekly injections, or herbal medications for seven (7) days prior to having your procedure. You may take vitamins.
• DO NOT drink alcohol for 24 hours before or after your procedure.
• DO NOT use items such as gum, hard candy, breath mints, smokeless tobacco, or illicit drugs such as marijuana on the day of your procedure.
• DO NOT smoke tobacco, marijuana, vape, or chew tobacco on the day of your procedure.
• DO NOT drink liquids that are not clear such as milk or creamer.
• DO NOT drink liquids that are red or purple in color.
• DO NOT eat solid food the day before your colonoscopy or the morning of your procedure.

• If you have dentures, you may be required to remove them for the procedure.
• Leave your valuables at home. If you have body piercings, you will be asked to remove them prior to the procedure for your safety.
• If you are a diabetic, do not take your diabetic medication the day of your procedure. Bring your medication with you so you can take it after your procedure.
• If you have asthma, please bring your inhaler with you.
• Take your usual prescribed medications with no more than two (2) tablespoons / one (1) ounce of water up to three (3) hours prior to your appointment time.

Have your prescription filled. Please follow the prep instructions listed below, not the instructions on the prep box.

If you routinely have less than 2 bowel movements per week then you will also need to purchase an 8.3 oz. bottle of Miralax. Begin taking a dose of Miralax twice a day 5 days prior to your procedure. Take the last dose of Miralax in the morning the day before your procedure.

AVOID raw fruits and vegetables, whole wheat/multigrain products, beans, nuts, popcorn and seeds.

You may only have clear liquids the entire day such as water, coffee, tea, broth, sodas, apple juice, Gatorade, Kool-aid, Jell-O, popsicles and hard candy. You may not have any solid food. It is important to drink extra clear liquids before your prep to maintain adequate hydration. Do not drink liquids that are not clear such as milk. Do not drink liquids that are red or purple in color.

• Use the mixing container to mix the contents of the Dose 1 pouch with 16 ounces of water and stir/shake until completely dissolved. This may take up to 2-3 minutes. The prep may be mixed up to 6 hours prior to your prep start time if refrigerated. Drink the entire contents within the next 30 minutes. A straw may help.